| Pittsburgh Penguins |
| #2 | Day 1 | 7/10/2025 | Pittsburgh Penguins @ New York Rangers | OTW | 5 - 4 (prol.) |
| #13 | Day 3 | 9/10/2025 | New York Islanders @ Pittsburgh Penguins | L | 4 - 2 |
| #29 | Day 5 | 11/10/2025 | New York Rangers @ Pittsburgh Penguins | OTL | 4 - 3 (prol.) |
| #56 | Day 8 | 14/10/2025 | Pittsburgh Penguins @ Anaheim Ducks | W | 6 - 4 |
| #71 | Day 10 | 16/10/2025 | Pittsburgh Penguins @ Los Angeles Kings | OTL | 2 - 3 (prol.) |
| #88 | Day 12 | 18/10/2025 | Pittsburgh Penguins @ San Jose Sharks | W | 4 - 3 |
| #101 | Day 15 | 21/10/2025 | Vancouver Canucks @ Pittsburgh Penguins | L | 4 - 1 |
| #114 | Day 17 | 23/10/2025 | Pittsburgh Penguins @ Florida Panthers | L | 2 - 4 |
| #134 | Day 19 | 25/10/2025 | Columbus Blue Jackets @ Pittsburgh Penguins | L | 7 - 4 |
| #148 | Day 21 | 27/10/2025 | St-Louis Blues @ Pittsburgh Penguins | L | 4 - 3 |
| #150 | Day 22 | 28/10/2025 | Pittsburgh Penguins @ Philadelphia Flyers | L | 2 - 4 |
| #173 | Day 24 | 30/10/2025 | Pittsburgh Penguins @ Minnesota Wild | W | 6 - 5 |
| #182 | Day 26 | 1/11/2025 | Pittsburgh Penguins @ Winnipeg Jets | L | 1 - 3 |
| #199 | Day 28 | 3/11/2025 | Pittsburgh Penguins @ Toronto Maple Leafs | L | 2 - 3 |
| #221 | Day 31 | 6/11/2025 | Washington Capitals @ Pittsburgh Penguins | L | 5 - 4 |
| #231 | Day 33 | 8/11/2025 | Pittsburgh Penguins @ New Jersey Devils | W | 2 - 0 |
| #245 | Day 34 | 9/11/2025 | Los Angeles Kings @ Pittsburgh Penguins | L | 5 - 3 |
| #279 | Day 39 | 14/11/2025 | Pittsburgh Penguins @ Nashville Predators | W | 5 - 0 |
| #296 | Day 41 | 16/11/2025 | Nashville Predators @ Pittsburgh Penguins | L | 4 - 2 |
| #332 | Day 46 | 21/11/2025 | Minnesota Wild (7-12-1) @ Pittsburgh Penguins (6-11-2) | | |
| #340 | Day 47 | 22/11/2025 | Seattle Kraken (7-9-2) @ Pittsburgh Penguins (6-11-2) | | |
| #366 | Day 51 | 26/11/2025 | Buffalo Sabres (4-8-6) @ Pittsburgh Penguins (6-11-2) | | |
| #388 | Day 53 | 28/11/2025 | Pittsburgh Penguins (6-11-2) @ Columbus Blue Jackets (9-9-0) | | |
| #396 | Day 54 | 29/11/2025 | Toronto Maple Leafs (15-4-0) @ Pittsburgh Penguins (6-11-2) | | |
| #407 | Day 56 | 1/12/2025 | Pittsburgh Penguins (6-11-2) @ Philadelphia Flyers (9-8-1) | | |
| #428 | Day 59 | 4/12/2025 | Pittsburgh Penguins (6-11-2) @ Tampa Bay Lightning (3-14-1) | | |
| #456 | Day 62 | 7/12/2025 | Pittsburgh Penguins (6-11-2) @ Dallas Stars (12-5-2) | | |
| #470 | Day 64 | 9/12/2025 | Anaheim Ducks (7-9-2) @ Pittsburgh Penguins (6-11-2) | | |
| #484 | Day 66 | 11/12/2025 | Montreal Canadiens (15-3-0) @ Pittsburgh Penguins (6-11-2) | | |
| #497 | Day 68 | 13/12/2025 | San Jose Sharks (11-5-3) @ Pittsburgh Penguins (6-11-2) | | |
| #509 | Day 69 | 14/12/2025 | Utah Mammoth (6-11-1) @ Pittsburgh Penguins (6-11-2) | | |
| #524 | Day 71 | 16/12/2025 | Edmonton Oilers (12-7-1) @ Pittsburgh Penguins (6-11-2) | | |
| #537 | Day 73 | 18/12/2025 | Pittsburgh Penguins (6-11-2) @ Ottawa Senators (8-8-3) | | |
| #556 | Day 75 | 20/12/2025 | Pittsburgh Penguins (6-11-2) @ Montreal Canadiens (15-3-0) | | |
| #566 | Day 76 | 21/12/2025 | Montreal Canadiens (15-3-0) @ Pittsburgh Penguins (6-11-2) | | |
| #575 | Day 78 | 23/12/2025 | Pittsburgh Penguins (6-11-2) @ Toronto Maple Leafs (15-4-0) | | |
| #604 | Day 83 | 28/12/2025 | Pittsburgh Penguins (6-11-2) @ Chicago Blackhawks (10-7-1) | | |
| #619 | Day 85 | 30/12/2025 | Carolina Hurricanes (5-12-1) @ Pittsburgh Penguins (6-11-2) | | |
| #635 | Day 87 | 1/1/2026 | Detroit Red Wings (7-10-2) @ Pittsburgh Penguins (6-11-2) | | |
| #644 | Day 89 | 3/1/2026 | Pittsburgh Penguins (6-11-2) @ Detroit Red Wings (7-10-2) | | |
| #658 | Day 90 | 4/1/2026 | Pittsburgh Penguins (6-11-2) @ Columbus Blue Jackets (9-9-0) | | |
| #687 | Day 94 | 8/1/2026 | New Jersey Devils (11-6-1) @ Pittsburgh Penguins (6-11-2) | | |
| #698 | Day 96 | 10/1/2026 | Calgary Flames (7-11-2) @ Pittsburgh Penguins (6-11-2) | | |
| #712 | Day 97 | 11/1/2026 | Pittsburgh Penguins (6-11-2) @ Boston Bruins (13-5-2) | | |
| #726 | Day 99 | 13/1/2026 | Tampa Bay Lightning (3-14-1) @ Pittsburgh Penguins (6-11-2) | | |
| #741 | Day 101 | 15/1/2026 | Philadelphia Flyers (9-8-1) @ Pittsburgh Penguins (6-11-2) | | |
| #760 | Day 103 | 17/1/2026 | Columbus Blue Jackets (9-9-0) @ Pittsburgh Penguins (6-11-2) | | |
| #772 | Day 105 | 19/1/2026 | Pittsburgh Penguins (6-11-2) @ Seattle Kraken (7-9-2) | | |
| #791 | Day 107 | 21/1/2026 | Pittsburgh Penguins (6-11-2) @ Calgary Flames (7-11-2) | | |
| #800 | Day 108 | 22/1/2026 | Pittsburgh Penguins (6-11-2) @ Edmonton Oilers (12-7-1) | | |
| #822 | Day 111 | 25/1/2026 | Pittsburgh Penguins (6-11-2) @ Vancouver Canucks (11-8-1) | | |
| #850 | Day 115 | 29/1/2026 | Chicago Blackhawks (10-7-1) @ Pittsburgh Penguins (6-11-2) | | |
| #861 | Day 117 | 31/1/2026 | New York Rangers (11-4-5) @ Pittsburgh Penguins (6-11-2) | | |
| #877 | Day 119 | 2/2/2026 | Ottawa Senators (8-8-3) @ Pittsburgh Penguins (6-11-2) | | |
| #888 | Day 120 | 3/2/2026 | Pittsburgh Penguins (6-11-2) @ New York Islanders (8-10-1) | | |
| #903 | Day 122 | 5/2/2026 | Pittsburgh Penguins (6-11-2) @ Buffalo Sabres (4-8-6) | | |
| #922 | Day 143 | 26/2/2026 | New Jersey Devils (11-6-1) @ Pittsburgh Penguins (6-11-2) | | |
| #934 | Day 145 | 28/2/2026 | Pittsburgh Penguins (6-11-2) @ New York Rangers (11-4-5) | | |
| #947 | Day 146 | 1/3/2026 | Las Vegas Golden Knights (13-4-1) @ Pittsburgh Penguins (6-11-2) | | |
| #959 | Day 148 | 3/3/2026 | Pittsburgh Penguins (6-11-2) @ Boston Bruins (13-5-2) | | |
| #977 | Day 150 | 5/3/2026 | Buffalo Sabres (4-8-6) @ Pittsburgh Penguins (6-11-2) | | |
| #993 | Day 152 | 7/3/2026 | Philadelphia Flyers (9-8-1) @ Pittsburgh Penguins (6-11-2) | | |
| #1002 | Day 153 | 8/3/2026 | Boston Bruins (13-5-2) @ Pittsburgh Penguins (6-11-2) | | |
| #1018 | Day 155 | 10/3/2026 | Pittsburgh Penguins (6-11-2) @ Carolina Hurricanes (5-12-1) | | |
| #1039 | Day 157 | 12/3/2026 | Pittsburgh Penguins (6-11-2) @ Las Vegas Golden Knights (13-4-1) | | |
| #1054 | Day 159 | 14/3/2026 | Pittsburgh Penguins (6-11-2) @ Utah Mammoth (6-11-1) | | |
| #1067 | Day 161 | 16/3/2026 | Pittsburgh Penguins (6-11-2) @ Colorado Avalanche (13-6-0) | | |
| #1078 | Day 163 | 18/3/2026 | Pittsburgh Penguins (6-11-2) @ Carolina Hurricanes (5-12-1) | | |
| #1099 | Day 166 | 21/3/2026 | Winnipeg Jets (12-6-0) @ Pittsburgh Penguins (6-11-2) | | |
| #1112 | Day 167 | 22/3/2026 | Carolina Hurricanes (5-12-1) @ Pittsburgh Penguins (6-11-2) | | |
| #1126 | Day 169 | 24/3/2026 | Colorado Avalanche (13-6-0) @ Pittsburgh Penguins (6-11-2) | | |
| #1138 | Day 171 | 26/3/2026 | Pittsburgh Penguins (6-11-2) @ Ottawa Senators (8-8-3) | | |
| #1156 | Day 173 | 28/3/2026 | Dallas Stars (12-5-2) @ Pittsburgh Penguins (6-11-2) | | |
| #1173 | Day 175 | 30/3/2026 | Pittsburgh Penguins (6-11-2) @ New York Islanders (8-10-1) | | |
| #1183 | Day 176 | 31/3/2026 | Detroit Red Wings (7-10-2) @ Pittsburgh Penguins (6-11-2) | | |
| #1192 | Day 178 | 2/4/2026 | Pittsburgh Penguins (6-11-2) @ Tampa Bay Lightning (3-14-1) | | |
| #1211 | Day 180 | 4/4/2026 | Florida Panthers (14-2-2) @ Pittsburgh Penguins (6-11-2) | | |
| #1223 | Day 181 | 5/4/2026 | Florida Panthers (14-2-2) @ Pittsburgh Penguins (6-11-2) | | |
| #1251 | Day 185 | 9/4/2026 | Pittsburgh Penguins (6-11-2) @ New Jersey Devils (11-6-1) | | |
| #1263 | Day 187 | 11/4/2026 | Washington Capitals (12-5-1) @ Pittsburgh Penguins (6-11-2) | | |
| #1276 | Day 188 | 12/4/2026 | Pittsburgh Penguins (6-11-2) @ Washington Capitals (12-5-1) | | |
| #1299 | Day 190 | 14/4/2026 | Pittsburgh Penguins (6-11-2) @ St-Louis Blues (8-10-1) | | |
